Safia Shaikh, MD

Safia Shaikh, MD

Instructor in Medicine

Dr. Safia Shaikh is an Instructor in the Division of Hospital Medicine since July 2022. She is originally from Pakistan and earned her medical degree from Liaquat University of Medical and Health Sciences. After completing her residency at Dow University Health Sciences, she relocated to the USA. Dr. Shaikh finished her internship and residency at SSM Health St Mary’s Hospital in St. Louis. Currently, she is actively engaged in academic pursuits, pursuing a master’s in clinical sciences, focusing on general internal medicine and cardiovascular care. Her commitment to research is evident through numerous peer-reviewed publications and presentations. Dr. Shaikh is also keenly interested in Point-of-Care Ultrasound (POCUS). Dr. Shaikh’s diverse interests converge in her dedication to providing high-quality patient care within the Division of Hospital Medicine.


Medical Degree: Bachelor of Medicine and Bachelor of Surgery (MBBS), Liaquat University of Medical and Health Sciences, Sindh, Pakistan (2013)

Residency, Internal Medicine: Internal Medicine Residency, Dow University of Health Sciences, Karachi, Pakistan (2017)

Residency, Internal Medicine: SSM Health St Mary’s Hospital, St Louis, MO (2022)

Clinical Interests

Hospital medicine, inpatient care, and cardiology, quality improvement

Research Interests

Interested in research involving hospital medicine and quality improvement, with a special interest in Cardiology. Interested in cost effective medicine focused for patient care and measures to decrease readmission rate. 


Peer Reviewed Manuscripts:

Shaikh S, Mohamed MMG, Osman M, Kheiri B. Meta-Analysis Comparing Direct Oral Anticoagulants Versus Vitamin K Antagonists in Patients with Atrial Fibrillation Who Underwent Bioprosthetic Valve Replacement. Am J Cardiol. 2022.

Mohamed MMG, Shaikh S, Osman M, Kheiri B. Meta-Analysis of One-Month Dual Antiplatelet Therapy Versus Standard Dual Antiplatelet Therapy in Patients Undergoing Percutaneous Coronary Intervention. Am J Cardiol. 2021 Dec 31:S0002-9149(21)01160-7. doi: 10.1016/j.amjcard.2021.11.035. Epub ahead of print. PMID: 34980361.

Oyenuga M, Shaikh S, Harris B, Sinha J, Lacasse A. Recurrent neutropenia and chronic diarrhea following thymectomy: the good, the bad, and the ugly. J Community Hosp Intern Med Perspect. 2021 Mar 23;11(2):263-265. doi: 10.1080/20009666.2021.1877400. PMID: 33889334; PMCID: PMC8043559.

Mohamed MMG, Shaikh S, Osman M, Kheiri B. Meta-Analysis of Sodium-Glucose Cotransporter 2 Inhibitors in Heart Failure Patients Without Diabetes. Am J Cardiol. 2021 Jun 1;148:175-176. doi: 10.1016/j.amjcard.2021.03.001. Epub 2021 Mar 6. PMID: 33689699.

Shaikh S, Gonzalez-Zapata A, Mujeeb A, Rauf A, Thekkemuriyil D. Asymptomatic HyperCKemia: A Diagnostic Trap. Cureus. 2021 Jan 19;13(1):e12791. doi: 10.7759/cureus.12791. PMID: 33628661; PMCID: PMC7891676.

Shaikh S, Mohamed MM, Mujeeb A, Shaikh F, Harris B. Euglycemic Diabetic Ketoacidosis Precipitated by a Keto Diet: Importance of Dietary History in Diagnosis. Cureus. 2020 Sep 2;12(9):e10199. doi: 10.7759/cureus.10199. PMID: 33033677; PMCID: PMC7532873.