Monique Bruinsma, MD

Monique Bruinsma, MD

Assistant Professor of Medicine

Monique Bruinsma, MD, is an Assistant Professor of Medicine in the Division of Hospital Medicine.  She received her medical degree, masters in immunology, and residency training at Washington University/BJH.  In her clinical endeavors, she cares for acutely ill hospitalized medicine patients.   She has an interest in using information technology to improve the efficiency and safety of patient care.  She also fosters the development of physician trainees by providing didactic teaching as well as attending frequently on the general medicine teaching service.


  • BS, Chemistry: Duke University, Durham NC (2004)
  • Medical Degree: Washington University School of Medicine, St. Louis, MO (2016)
  • Residency, Internal Medicine: Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, MO (2019 )

Clinical Interests

Hospital Medicine, inpatient care


Peer Reviewed

Pei B, Zhao M, Miller BC, Vela JL, Bruinsma MW, Virgin HW, Kronenbergy M, 2015. Invariant NKT cells require autophagy to coordinate proliferation and survival signals during differentiation. J Immunol. 194 (12): 5872-84.

Xu X, Araki K,  Li S, Han JH, Ye L,Tan WG, Konieczny BT, Bruinsma MW, Martinez J, Pearce EL, Green DR, Jones DP, Virgin HW, Ahmed R, 2014. Autophagy is essential for effector CD8 T cell survival and memory formation. Nature Immunol. 15 (12): 1152-61.

Hwang S, Maloney NS, Bruinsma MW, Goel G, Duan E, Zhang L, Shrestha B, Diamond MS, Dani A, Sosnovtsev SV, Green KY, Lopez-Otin C, Xavier RJ, Thackray LB, Virgin HW, 2012. Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma. Cell Host Microbe. 11(4):397-409.

Iben JR, Epstein JA, Bayfield MA, Bruinsma MW, Hasson S, Bacikova D, Ahmad D, Rockwell D, Kittler EL, Zapp ML, Maraia RJ, 2011. Comparative whole genome sequencing reveals phenotypic tRNA gene duplication in spontaneous Schizosaccharomyces pombe La mutants. Nucleic Acids Res. 39(11):4728-42.

Villalobos V, Naik S, Bruinsma M, Dothager RS, Pan MH, Samrakandi M, Moss B, Elhammali A, Piwnica-Worms D, 2010. Dual-color click beetle luciferase heteroprotein fragment complementation assays. Chem Biol. 17(9):1018-29.

Kirkbride KC, Townsend TA, Bruinsma MW, Barnett JV, Blobe GC, 2008. Bone Morphogenetic Proteins Signal through the Transforming Growth Factor-beta Type III Receptor. J Biol Chem. 283(12):7628-37.

You HJ, Bruinsma MW, How T, Ostrander JH, Blobe GC, 2007. The type III TGF-beta receptor signals through both Smad3 and the p38 MAP kinase pathways to contribute to inhibition of cell proliferation. Carcinogenesis. 28(12):2491-500.

Park JM, Kohn MJ, Bruinsma MW, Vech C, Intine RV, Fuhrmann S, Grinberg A, Mukherjee I, Love PE, Ko MS, DePamphilis ML, Maraia RJ, 2006. The multifunctional RNA-binding protein La is required for mouse development and for the establishment of embryonic stem cells. Mol Cell Biol. 26(4):1445-51.

Oral Presentations

Bruinsma MW. Urinary Tract Infections: Acute Simple Cystitis. Washington University Internal Medicine Ambulatory Morning Report. March 18, 2019.

Bruinsma, MW, Benjamin Buettner, Brandt Lydon, Elaine Shao. Medication Errors: The dark side of information technology. Washington University Internal Medicine Patient Safety Quality Improvement Conference. February 7, 2019.

Bruinsma, MW. New-Onset Cardiovascular Morbidity in Older Adults with Stage I to III Colorectal Cancer. Washington University Internal Medicine Geriatrics Journal Club. July 23, 2018.

Bruinsma, MW. Falls: Progressive Supranuclear Palsy. Washington University Internal Medicine Resident Report. April 25, 2018.

Bruinsma, MW. Liver Failure: Radiologically Occult Liver Metastasis. Washington University Internal Medicine Resident Report. November 29, 2017.

Bruinsma, MW. Randomized Trial of Icatibant for Angiotensin-Converting Enzyme Inhibitor—Induced Upper Airway Angioedema. Washington University Internal Medicine Resident Journal Club. October 31, 2017.

Bruinsma, MW. Rituximab versus Cyclophosphamide for ANCA-Associated Vasculitis. Washington University Internal Medicine Intern Journal Club. May 23, 2017.

Poster Presentations

Bruinsma MW, Fisher T. Stand up to Falls: A proposed project to prevent falls in the New Zealand elderly, an example of proactive healthcare. Forum for International Health and Tropical Medicine Global Health Symposium. 2016.

Bruinsma MW, Virgin HW. Cell-type specific investigation of Crohn’s disease susceptibility gene Atg16L1 in inflammation. Keystone Symposium Autophagy. 2011.