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Derek Yee, MD

Instructor in Medicine




  • B.S., Biomedical Engineering: John Hopkins University, Baltimore, MD (2010)
  • Medical Degree: Rutgers - New Jersey Medical School, Newark, NJ (2014)
  • Residency, Internal Medicine: Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, MO (2017)

Board Certifications

  • American Board of Internal Medicine

Clinical Interests

Hospital medicine, inpatient care

Peer Reviewed Publications

Schirone L, Forte M, Palmerio S, Yee D, Nocella C, Angelini F, Pagano F, Schiavon S, Bordin A, Carrizzo A, Vecchione C, Valenti V, Chimenti I, De Falco E, Sciarretta S, Frati G. A Review of the Molecular Mechanisms Underlying the Development and Progression of Cardiac Remodeling. Oxid Med Cell Longev. 2017;2017:3920195. Epub 2017 Jul 2.

Forte M, Palmerio S, Yee D, Frati G, Sciarretta S. Functional Role of Nox4 in Autophagy. Adv Exp Med Biol. 2017 May;982:307-326.

Sciarretta S, Zhai P, Maejima Y, Del Re DP, Nagarajan N, Yee D, Liu T, Magnuson MA, Volpe M, Frati G, Li H, Sadoshima J. mTORC2 regulates cardiac response to stress by inhibiting MST1. Cell Rep. 2015 Apr; 11(1):125-36.

Sciarretta S, Yee D, Ammann P, Nagarajan N, Volpe M, Frati G, Sadoshima J. The role of NADPHoxidase in the regulation of autophagy in cardiomyocytes. Clin Sci. 2015 Apr; 128(7):387-403.

Sciarretta S, Yee D, Shenoy V, Nagarajan N, Sadoshima J. The importance of autophagy in cardioprotection. High Blood Press Cardiovasc Prev. 2014 Mar; 21(1):21-8.

Yee D, Hanjaya-Putra D, Bose V, Luong E, Gerecht S. Hyaluronic acid hydrogels support cord-like structures from endothelial colony-forming cells. Tissue Eng Part A. 2011 May; 17(9-10):1351-61.

Hanjaya-Putra D, Yee J, Ceci D, Truitt R, Yee D, Gerecht S. Vascular endothelial growth factor and substrate mechanics regulate in vitro tubulogenesis of endothelial progenitor cells. J Cell Mol Med. 2010 Oct; 14(10):2436-47.

Abstracts and Presentations

Yee D, Novak E, Platts A, Nassif M, LaRue S, Vader J. Comparison of the Kansas City Cardiomyopathy Questionnaire and Minnesota Living With Heart Failure Questionnaire in Predicting Heart Failure Outcomes. American College of Cardiology. April 2016. Poster.

Sciarretta S, Nagarajan N, Yee D, Zhai P, Umpathi P, Brady CD, Volpe M, Frati G, Sadoshima J. Activation of PKR-Like Endoplasmic Reticulum Kinase is Required for Autophagy Stimulation and Cardiomyocyte Survival During Acute Myocardial Ischemia. Circulation. 2014; 130:A15689.

Sciarretta S, Zhai P, Shao D, Yee D, Zablocki D, Terada LS, Volpe M, Sadoshima J. Nox4-Derived ROS Production in the Endoplasmic Reticulum Promotes Autophagy during Cardiomyocyte Nutrient Deprivation through the PHD4/ PERK Pathway. Circulation. 2013; 128:A16705.

Sciarretta S, Zhai P, Yee D, Volpe M, Sadoshima J. WW45, a Scaffold Protein, is a Positive Regulator of Mst1 and Stimulates Myocardial Injury Through the Suppression of YAP. Circulation. 2013; 128:A16325.

Dean ED, Dai C, Poffenberger G, Reyes AR, Wakefield G, Yee D, McLeod K, Gu W, Yan H, Powers AC. Human and mouse alpha cells proliferate after glucagon receptor blockade. Keystone Symposium on Advances in Islet Biology. March 2012. Poster.

Yee D, McLeod K, Dean ED, Poffenberger G, Dai C, Robledo A, Powers AC. Human alpha-islet cells proliferate in vivo after treatment with glucagon receptor antibody. NIDDK Diabetes Research Centers – Medical Student Research Symposium. August 2011. Poster.